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| Antigenic Specificity | Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (aa 20-764) |
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| Clone | 4B4 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µL |
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| Concentration | n/a |
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| Applications | ELISA,Flow Cytometry (FACS),Immunocytochemistry (ICC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | KDR has also been designated as VEFR-2 (Vascular endothelial growth factor receptor 2), CD309 (cluster of differentiation 309) and Flk1 (fetal liver kinase 1). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. KDR is one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. |
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| Immunogen | Purified recombinant extracellular fragment of human KDR (AA 20-764) fused with hIgGFc tag expressed in HEK293 cells. |
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| Other Names | vegfr-2|KDR|6130401C07|Flk-1|Flk1|Krd-1|Ly73|VEGFR-2|VEGFR2|sVEGFR-2|Vegfr-2|CD309|FLK1|VEGFR|FLK-1|flk-1|FLK/KDR|flk1|flk1b|kdrb|si:busm1-205d10.1|si:ch211-254j6.1|si:ch211-278f21.4|wu:fc31a09|fk52c05|flk|kdr|kdra|vegfr2|vegfr4|vegr2|wu:fk52c05 |
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| Gene, Accession # | Gene ID: 3791 |
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| Catalog # | ABIN969231 |
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| Price | |
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| Order / More Info | Kinase insert Domain Receptor (A Type III Receptor tyrosine Kinase) (KDR) (aa 20-764) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 14996703, 11387210 |
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