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Antigenic Specificity | Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (Middle Region) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, dog, chicken, Xenopus laevis |
Isotype | n/a |
Format | purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction. Synonyms: Polyclonal CHRNB3 antibody, Anti-CHRNB3 antibody, cholinergic receptor, nicotinic, beta 3 antibody. |
Immunogen | CHRNB3 antibody was raised in rabbit using the middle region of CHRNB3 as the immunogen |
Other Names | NACHR|5730417K16Rik|Acrb3 |
Gene, Accession # | Gene ID: 380344,395604,1142,482837,108043,171131 |
Catalog # | ABIN926966 |
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Order / More Info | Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3) (Middle Region) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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