产品名称 Cholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN630117
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityCholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),Immunohistochemistry (IHC)
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DescriptionMutations in nAChRs are found in a rare form of nocturnal frontal lobe epilepsy . Previously, some nAChR mutations have been described that are associated with additional neurological features such as psychiatric disorders or cognitive defects. A new CHRNB2 mutation located in transmembrane region 3 (M3), outside the known ADNFLE mutation cluster. The CHRNB2 mutation I312M, which occurred de novo in twins, markedly increases the receptor's sensitivity to acetylcholine. Phenotypically, the mutation is associated not only with typical ADNFLE, but also with distinct deficits in memory. The cognitive problems are most obvious in tasks requiring the organization and storage of verbal information.
ImmunogenCHRNB2 antibody was raised using a synthetic peptide corresponding to a region with amino acids CKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLDDFTPSGEWD
Other NamesEFNL3|nAChRB2|NACHRB2|Acrb-2|Acrb2|C030030P04Rik|[b]2-nAchR
Gene, Accession #Gene ID: 1141
Catalog #ABIN630117
Price
Order / More InfoCholinergic Receptor, Nicotinic, beta 2 (Neuronal) (CHRNB2) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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