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Antigenic Specificity | Caspase Recruitment Domain Family, Member 8 (CARD8) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined. [provided by RefSeq] Synonyms: CARD8, CARDINAL, DACAR, DKFZp779L0366, Dakar, FLJ18119, FLJ18121, KIAA0955, MGC57162, NDPP, NDPP1, TUCAN |
Immunogen | Recombinant protein of human CARD8 |
Other Names | CARD8|CARDINAL|DACAR|DAKAR|NDPP|NDPP1|TUCAN |
Gene, Accession # | Gene ID: 22900 |
Catalog # | ABIN1512669 |
Price | |
Order / More Info | Caspase Recruitment Domain Family, Member 8 (CARD8) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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