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| Product Name | VU0483605 |
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| Description | A selective mGluR1 PAM (EC50s = 0.39 and 0.36 µM for human and rat receptors, respectively) with no activity as a mGlu4 PAM (EC50 >10 µM); potentiates a response to glutamate in wild-type cell lines stably expressing mGlu1 and partially restores the reduction in glutamate-mediated calcium signaling in a mutant cell model of schizophrenia |
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| Size | 1 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | Glutamate neuroscience metabotropic glutamate receptor mGluR1 positive allosteric modulator PAM schizophrenia biochemical signal transduction biochemistry intracellular signaling VU-0483605 selective mGlu1 reduction mediated calcium mutant cells CNS central nervous system |
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| Gene, Accession, CAS # | CAS: 1623101-11-0 |
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| Catalog # | 16941-1 |
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| Price | |
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| Order / More Info | VU0483605 from CAYMAN CHEMICAL COMPANY |
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| Product Specific References | n/a |
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