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Product Name | Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (AA 212-357) protein (His tag) |
Description | Programmed Cell Death Protein 4 (PDCD4) is a member of the PDCD4 family. PDCD4 and EIF4A1 form a heterotrimer. One molecule of PDCD4 binds two molecules of EIF4A1. PDCD4 takes part in apoptosis via inhibiting translation initiation and cap-dependent translation.PDCD4 promotes colonic neoplastic transformation and tumor invasion. PDCD4 is an important target for microrna R-21 in breast cancer cells. Shortage of PDCD4 expression is associated with colorectal cancer. Overexpression of PDCD4 in carcinoid cells results in inhibition of cell proliferation.Alternative Names: Programmed Cell Death Protein 4, Neoplastic Transformation Inhibitor Protein, Nuclear Antigen H731-Like, Protein 197/15a, PDCD4, H731 |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | h731|MGC69337|PDCD4|D19Ucla1|Ma3|Tis|Dug|H731 |
Gene, Accession, CAS # | Gene ID: 27250 |
Catalog # | ABIN1692137 |
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Order / More Info | Programmed Cell Death 4 (Neoplastic Transformation Inhibitor) (PDCD4) (AA 212-357) protein (His tag) from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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