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Product Name | WM3060 Purified Genomic DNA |
Description | DNA was prepared from cell line WM3060. WM3060 is a metastatic human melanoma cell line established from a metastatic site (left axillary nodes) in a 55-year-old male with level III malignant melanoma. The subject displayed VGP, and RGP with a tumor thickness of 3.0 mm. This cell line was derived from the same patient as the cell lines WM2013, and WM1960. This cell line contains a Q61K mutation at position 61 in the N-RAS gene which causes increased signaling via the extracellular signal-regulated MAPK/ERK kinase pathways to enhance proliferation. This cell line is wild type for BRAF, PTEN, c-KIT, and CDK4. WM3060 cells produce xenograft tumors when injected into immunocompromised mice. |
Size | 5 µg |
Concentration | 200 ng / µl |
Applications | Purified Genomic DNA is suitable for a number of molecular biology applications including but not limited to preparation of genomic libraries, PCR templates, DNA sequencing, DNA fingerprinting, and mutation analysis. |
Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
Gene, Accession, CAS # | n/a |
Catalog # | WM3060-02-0200 |
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Order / More Info | WM3060 Purified Genomic DNA from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |
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