| 产品详情 |
| Edit |   |
|---|
| Product Name | NIK, Recombinant, Human, GST-tag |
|---|
| Description | Purified (~70-90%). NIK is a mitogen-activated protein kinase kinase kinase 14 (MAP3K14), which binds to TRAF2 and stimulates NF-kappaB activity. NIK shares sequence similarity with several other MAPKK kinases and participates in NF-kappaB-inducing signalling cascade common to receptors of the tumor-necrosis/nerve-growth factor (TNF/NGF) family and to the interleukin-1 type-I receptor. NIK is expressed in primary human cells and in inflamed rheumatoid arthritis tissue and plays a selective role in signaling by the lymphotoxin-beta receptor. NIK is a therapeutic target in the immune and bone-destructive components of inflammatory arthritis. Source: Recombinant protein corresponding to human NIK, fused to GST-Tag at N-terminal expressed in Insect cells. Molecular Weight: ~108kD Specific Activity: 8nmol/min/mg as per activity assay protocol. Endotoxin: <1EU/ug (LAL) |
|---|
| Size | 10ug |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | NIK, Recombinant, Human, GST-Tag (NF-kappa-beta-inducing Kinase, Mitogen-Activated Protein Kinase Kinase Kinase 14, MAP3K14, HS, HSNIK, FTDCR1B) |
|---|
| Gene, Accession, CAS # | Accession: NM_003954 |
|---|
| Catalog # | 500310 |
|---|
| Price | |
|---|
| Order / More Info | NIK, Recombinant, Human, GST-tag from UNITED STATES BIOLOGICAL |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|