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| Product Name | WM373 Viable Cells (1 x10^6 cells) |
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| Description | WM373 is a metastatic human melanoma cell line that displays a pigmented morphology and grows in tight adherent dense colonies. This cell line was established from a left upper back metastasis site in a 49-year-old male with level IV superficial spreading melanoma. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. WM373 cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 1 mL |
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| Concentration | 1.25x10^6 |
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| Applications | The key applications of these cell lines include genetic studies, xenograft production, drug testing, and drug target discovery. These cell line models can be used in various biological assays, and for identifying critical target genes, and cell signaling pathways. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM373-01-0001 |
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| Order / More Info | WM373 Viable Cells (1 x10^6 cells) from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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