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| Product Name | WM1361A Non-Viable Cell Pellet |
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| Description | Non-viable cell pellet was generated from cell line WM1361A. WM1361A is a tumorigenic (VGP) primary melanoma cell line with competence for metastasis. These cells display mesenchymal morphology in culture. This cell line contains a Q61R mutation at position 61 in the N-RAS gene. The Q61R is the most common NRAS mutation found in melanoma that is thought to occur due to UV and radiation exposure. This mutation leads to production of a constitutively active N-RAS protein that directs cells to grow and divide constantly. This cell line also expresses PTEN loss of function including hemizygous PTEN deletion and is wild type for BRAF, c-KIT, and CDK4. WM1361A cells produce xenograft tumors when injected into immunocompromised mice. |
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| Size | 2 mg |
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| Concentration | 2.0 million cells |
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| Applications | Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation. |
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| Other Names | Human Melanoma, patient derived tumor, tumor models, skin cancer, xenograft |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | WM1361A-03-0002 |
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| Price | |
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| Order / More Info | WM1361A Non-Viable Cell Pellet from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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