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Antigenic Specificity | Von Willebrand Factor |
Clone | polyclonal |
Host Species | Sheep |
Reactive Species | human |
Isotype | n/a |
Format | IgG fraction |
Size | 1 mL |
Concentration | n/a |
Applications | . Anti-Human Von Willebrand Factor has been tested in CCIEP. May be useful in additional assays. Specific conditions for reactivity should be optimized by the end user. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This polyclonal antibody is directed against human von Willebrand Factor and is an IgG fraction purification. von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen. Anti-Human (VWF) Von Willebrand Factor Antibody is useful for researcher in cardiovascular, neoplastic, and connective tissue research. |
Immunogen | Anti-Human Von Willebrand Factor was produced in sheep by repeated immunizations with Human von Willebrand Factor Antigen (vWF), prepared from citrated human plasma, shown to be greater than 95% purity by SDS-PAGE. |
Other Names | Sheep Anti-Human Von Willebrand Factor Antibody, Sheep Anti-Von Willebrand Factor Antibody, Sheep Anti-VWF Antibody, Sheep Anti-Human VWF Antibody |
Gene, Accession # | VWF, Gene ID: 7450, UniProt: P04275, NCBI: NP 000543.2 |
Catalog # | 200-601-MC2 |
Price | |
Order / More Info | Von Willebrand Factor Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | Maor E (2010) Vascular smooth muscle cells ablation with endovascular non thermal irreversible electroporation |