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Antigenic Specificity | APP, N-terminus |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | immunoaffinity purified |
Size | 100 µg |
Concentration | 1 mg/mL |
Applications | Western Blot. Anti-APP Antibody is suitable for use in E,WB, and IHC. Expect a band approximately ~86.9 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-APP Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with APP with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with APP from other sources has not been determined. |
Immunogen | APP Antibody was produced from whole rabbit serum prepared by repeated immunizations with a peptide corresponding to amino acids of human amyloid A4 protein precursor (APP) corresponding to the n-terminus of the 4K Ab peptide generated by b- and g-secretases. The peptide sequences are identical to those of rabbit, pig, bovine, guinea pig, and chicken. |
Other Names | APP (AbNT), APP(AbNT),ABPP |
Gene, Accession # | Amyloid beta A4 protein, Gene ID: 351, NCBI: CAA30050, UniProt: P05067 |
Catalog # | 600-401-G76 |
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Order / More Info | APP, N-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | N Nagai, Y Ito. (2013) Excessive hydrogen peroxide enhances the attachment of amyloid ?1-42 in the lens epithelium of UPL rats, a hereditary model for cataracts. ScienceDirect Toxicology. Vol 315, 6 Jan 2014, Pages 55-64. |
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