| 产品详情 |
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| Antigenic Specificity | Apc11, C-terminus |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | delipidated & defibrinated |
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| Size | 100 µL |
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| Concentration | 85 mg/mL |
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| Applications | ELISA, Immunohistochemistry, Western Blot. This antibody reacts with human APC11 by western blot and immunoprecipitation. The antibody immunoprecipitates in vitro translated protein and protein from overexpressing cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins (APC2) does occur. A 9.8 kDa band corresponding to human APC11 is detected. Most cell lines or tissues expressing APC11 can be used as a positive control. Researchers should determine optimal titers for other applications. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This product reacts with human and mouse APC11. Cross reactivity may also occur with APC11 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2. |
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| Immunogen | This antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH. |
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| Other Names | rabbit anti-Apc11 Antibody, Anaphase promoting complex subunit 11 homolog antibody, APC11 anaphase promoting complex subunit 11 homolog antibody, Cyclosome subunit 11 antibody, Hepatocellular carcinoma associated RING finger protein antibody, HSPC 214 antibody, Apc |
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| Gene, Accession # | ANAPC11, Gene ID: 51529, NCBI: 19924286, UniProt: Q9NYG5 |
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| Catalog # | 100-401-A15 |
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| Price | |
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| Order / More Info | Apc11, C-terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | Ohta T,Michel JJ,Xiong Y, (1999) Association with cullin partners protects ROC proteins from proteasome-dependent degradation. Oncogene 18:48, 6758-6766.Furukawa M,Ohta T,Xiong Y, (2002) Activation of UBC5 ubiquitin-conjugating enzyme by the RING finger of ROC1 and assembly of active ubiquitin ligases by all cullins. J Biol Chem 277:18, 15758-15765. |
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