| 产品详情 |
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| Antigenic Specificity | GFAP, C-Terminus |
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| Clone | S206A-8 |
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| Host Species | Mouse |
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| Reactive Species | human, rat, mouse |
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| Isotype | IgG1 |
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| Format | Protein G purified |
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| Size | 100 µg |
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| Concentration | 1.0 mg/ml |
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| Applications | Immunohistochemistry, IF Microscopy, Western Blot. Anti-GFAP Antibody is suitable for use in Western blot, Immunohistochemistry, and Immunocytochemistry. Expect a band approximately ~50 kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Anti-GFAP Antibody was purified from concentrated tissue culture supernate by Protein G chromatography. A BLAST analysis was used to suggest cross-reactivity with rat and mouse based on 100% homology with the immunizing sequence. Cross-reactivity with GFAP-R416W and other GFAP mutant proteins can be expected. The 50 kDa type III intermediate filament protein glial fibrillary acidic protein (GFAP) is a major structural component of astrocytes. GFAP associates with the calcium binding protein annexin II-p2 and S-100. Association with these proteins together with phosphorylation regulates GFAP polymerization. Astroycytes respond to brain injury by proliferatin (astrogliosis), and one of the first events to occur during astrocyte proiliferation is increased GFAP expression. Interestingly, antibodies to GFAP have been detected in individuals with dementia. Anti-GFAP is ideal for investigators involved in Neuroscience Research, including Alexander Disease, Oligodendroglioma, Cytoskleton Remolding Neurofilaments and PIP3/AKT Signaling. |
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| Immunogen | Anti-GFAP Antibody was produced in mice by repeated immunizations with a synthetic peptide corresponding to amino acids 411-422 (KTVEMRDGEVIK) of human GFAP. |
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| Other Names | Glial fibrillary acidic protein, Intermediate filament protein, Astrocyte, gfapl, DKFZp459C0729, MGC139638, FLJ45472, AI836096, GFAP antibody |
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| Gene, Accession # | GFAP, Gene ID: 2670, UniProt: P14136 |
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| Catalog # | 200-301-W55 |
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| Price | |
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| Order / More Info | GFAP, C-Terminus Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
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| Product Specific References | n/a |
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