产品详情 |
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Antigenic Specificity | Hepatitis D |
Clone | M8.13 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | ion exchange purified, no preservative |
Size | 1 mg |
Concentration | 1.0mg/mL |
Applications | ELISA. Anti-HDV has been tested in ELISA. Can be used as the coating antibody in conjunction with Anti-Human Hepatitis D (MOUSE) Antibodies (p/n's 200-301-MB7 and 200-301-MB8). May be useful in additional assays. Specific conditions for reactivity should be optimized by the end user. |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | This purified monoclonal antibody is directed against hepatitis D and was purified by Ion exchange chromatography. Purity was confirmed by ELISA to be >95% pure. Hepatitis D (HDV) is one of the five hepatitis viruses of the liver. Hepatitis D Virus (hepatitis delta) is considered a sub viral satellite because it can only propagate in the presence of hepatitis B virus. It can be transmitted as a coinfection simultaneously with HBV or as a superinfection. Both superinfection and coinfection with HDV results in more severe complications compared to infection with HBV alone. These complications include a greater likelihood of experiencing liver failure in acute infections and a rapid progression to liver cirrhosis, with an increased risk of developing liver cancer in chronic infections. In combination with hepatitis B virus, hepatitis D has the highest fatality rate of all the hepatitis infections, at 20%. With a genome of approximately 1700 nucleotides, HDV is the smallest virus known to infect animals. It has been proposed that HDV may have originated from a class of plant pathogens called viroids, which are much smaller than viruses. A significant difference between viroids and HDV is that, while viroids produce no proteins, HDV is known to produce one protein, namely HDAg. It comes in two forms; a 27kDa large-HDAg, and a small-HDAg of 24kDa. Anti-Human (HDV) Hepatitis D Antibody is useful for researchers interested in infectious disease. |
Immunogen | Mouse monoclonal Anti-Human Hepatitis D [M8.13] was produced in mice by repeated immunizations with Purified HDV strain virions. |
Other Names | HDV, Hepatitis D, mouse anti-HDV, mouse anti-Hepatitis D, a-Hu HDV |
Gene, Accession # | n/a |
Catalog # | 200-301-MB6 |
Price | |
Order / More Info | Hepatitis D Antibody from ROCKLAND IMMUNOCHEMICALS INC. |
Product Specific References | n/a |
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