| 产品详情 |
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| Product Name | Mitochondrial Antiviral Signaling Protein (MAVS) peptide |
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| Description | Double-stranded RNA viruses are recognised in a cell type-dependent manner by the transmembrane receptor TLR3 or by the cytoplasmic RNA helicases MDA5 and RIGI (ROBO3). These interactions initiate signaling pathways that differ in their initial steps but converge in the activation of the protein kinases IKKA (CHUK) and IKKB (IKBKB), which activate NFKB, or TBK1 and IKKE (IKBKE), which activate IRF3. Activated IRF3 and NFKB induce transcription of IFNB (IFNB1). For the TLR3 pathway, the intermediary molecule before the pathways converge is the cytoplasmic protein TRIF (TICAM1). For RIGI, the intermediary protein is mitochondria-bound VISA. |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP) |
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| Other Names | VISA|HISPPD2A|IP6K|IPS1|VIP1|hsVIP1|CARDIF|IPS-1|D430028G21Rik|Visa|cardif |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN938153 |
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| Price | |
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| Order / More Info | Mitochondrial Antiviral Signaling Protein (MAVS) peptide from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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| 产品资料 |
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