产品详情 |
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Antigenic Specificity | CD22 |
Clone | RFB4 |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine) drug conjugate |
Size | n/a |
Concentration | n/a |
Applications | n/a |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Anti-CD22 (clone RFB4)-SMCC-DM1 ADC. This Antibody-Drug Conjugate (ADC) product is comprised of an anti-CD22 monoclonal antibody (clone RFB4) conjugated via a Mc-VC-PABC linker to MMAE. The MMAE is targeted to certain cancers by immunerecognition and delivered into cancer cells via receptor mediated endocytosis. Within the cell, MMAE binds to tubulins, interrupts microtubule dynamics, and subsequently, induces cell death. |
Immunogen | n/a |
Other Names | n/a |
Gene, Accession # | Gene ID: 933, UniProt: P20273 |
Catalog # | ADC-W-190 |
Price | |
Order / More Info | CD22 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
产品资料 |
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