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Product Name | Recombinant Human Histone-binding protein RBBP7 (RBBP7) |
Description | Purity > 90% as determined by SDS-PAGE. MW: 63.8kDa. Full Length: 1-425aa. N-terminal 6xHis-SUMO-tagged. Homo sapiens (Human). Core histone-binding subunit that may target chromatin rodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assbly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome rodeling and histone deacetylase complex (the NuRD complex), which promotes transcriptional repression by histone deacetylation and nucleosome rodeling; and the PRC2/EED-EZH2 complex, which promotes repression of homeotic genes during development; and the NURF (nucleosome rodeling factor) complex. |
Size | 100ug |
Concentration | n/a |
Applications | RUO |
Other Names | Histone acetyltransferase type B subunit 2Nucleosome-remodeling factor subunit RBAP46Retinoblastoma-binding protein 7; RBBP-7Retinoblastoma-binding protein p46 |
Gene, Accession, CAS # | RBBP7, UniProt: Q16576 |
Catalog # | RPC23027 |
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Order / More Info | Recombinant Human Histone-binding protein RBBP7 (RBBP7) from BIOMATIK |
Product Specific References | n/a |
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