产品名称 Baculoviral IAP Repeat Containing 2 (BIRC2) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1512638
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityBaculoviral IAP Repeat Containing 2 (BIRC2)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, human
Isotypen/a
Formataffinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),Immunohistochemistry (IHC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe inhibitor of apoptosis protein (IAP) family consists of an evolutionarily conserved group of apoptosis inhibitors containing a conserved 70 AA BIR (baculovirus inhibitor repeat) domain. Human members of this family include c-IAP1, c-IAP2, XIAP, survivin, livin, and NAIP. Overexpression of IAP family members, particularly survivin and livin, in cancer cell lines and primary tumors suggests an important role for these proteins in cancer progression. In general, the IAP proteins function through direct interactions to inhibit the activity of several caspases, including caspase-3, caspase-7, and caspase-9. In addition, binding of IAP family members to the mitochondrial protein Smac blocks their interaction with caspase-9, thereby allowing the processing and activation of the caspase.Synonyms: BIRC2, API1, HIAP2, Hiap-2, MIHB, RNF48, cIAP1
ImmunogenRecombinant protein of human BIRC2
Other NamesApi1|Api2|IAP1|IAP2|MIHB|MIHC|Birc2|HIAP2|MIAP1|MIAP2|RNF49|cIAP1|cIAP2|cIAP-1|cIAP-2|AW107670|ciap-1|API1|Hiap-2|RNF48|c-IAP1|ITA|AW146227|Birc3|HIAP1|mcIAP1|rIAP1|RGD1559914
Gene, Accession #Gene ID: 329,11797,60371
Catalog #ABIN1512638
Price
Order / More InfoBaculoviral IAP Repeat Containing 2 (BIRC2) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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