| 产品详情 |
| Edit |   |
|---|
| Product Name | Interleukin 17A (IL17A) (AA 26-158) protein |
|---|
| Description | Interleukin-17A, (also known as CTLA-8) is a T cell-expressed pleiotropic cytokine that exhibits a high degree of homology to a protein encoded by the ORF13 gene of herpesvirus Saimiri. cDNA clones encoding IL-17 have been isolated from activated rat, mouse and human T cells. IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. Recombinant murine IL-17A is a 15-20kDa glycosylated cytokine of 133 amino acid polypeptide chain that plays an important role in antimicrobial and chronic inflammation. IL-17 exhibits multiple biological activities on a variety of cells including the induction of IL-6 and IL-8 production in fibroblasts, the enhancement of surface expression of ICAM-1 in fibroblasts, activation of NF-kappaB and costimulation of T cell proliferation.Synonyms: IL-17A, CTLA-8 |
|---|
| Size | 50 µg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Il17|IL17A|CTLA8|IL-17|IL-17A|IL17|Ctla-8|Ctla8|CTLA-8|ChIL-17|IL-17F |
|---|
| Gene, Accession, CAS # | Gene ID: 16171 |
|---|
| Catalog # | ABIN2018069 |
|---|
| Price | |
|---|
| Order / More Info | Interleukin 17A (IL17A) (AA 26-158) protein from ANTIBODIES-ONLINE GmbH |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|