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Product Name | Interleukin 10 (IL10) (AA 19-178) (Active) protein |
Description | Interleukin-10 (IL-10), initially known as Cytokine Synthesis Inhibitory Factor (CSIF), belongs to the IL-10 family and shares more than 80% sequence homology with the Epstein-Barr Virus protein BCRFI. It is produced by many immune cells, such as T-cells, macrophages, mast cells and dendritic cells. It is usually secreted as a homodimer and, upon binding to its receptor, inhibits the synthesis of a number of cytokines, including IFN-gamma, IL-2, IL-3, TNF and GM-CSF, by activated macrophages and Th2 cells. It also displays the ability to suppress Antigen-Presenting Cell (APC) function. The net effect of Interleukin-10 appears to be inhibitory, however, stimulatory effects, such as stimulation of B cell maturation and antibody production, are also reported.Synonyms: B-TCGF, CSIF, TGIF |
Size | 50 µg |
Concentration | n/a |
Applications | n/a |
Other Names | CSIF|GVHDS|IL-10|IL10A|TGIF|Il-10|IL10X |
Gene, Accession, CAS # | Gene ID: 16153 |
Catalog # | ABIN2018045 |
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Order / More Info | Interleukin 10 (IL10) (AA 19-178) (Active) protein from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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