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| Antigenic Specificity | RT1 Class II, Locus Bb (RT1-BB) |
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| Clone | OX-6 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat |
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| Isotype | IgG1 |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | anti-rat RT1.B monoclonal antibody recognizes Ia from all rat strains tested. It labels a monomorphic determinant of the rat Ia antigen present on the majority of peripheral B lymphocytes, dendritic cells, some macrophages, and certain epithelial cells (2,3,4) but not peripheral T lymphocytes. (4) This antibody also cross reacts with murine Ia antigens (particularly with k and s haplotypes). Analysis of recombinant strains shows that the determinant maps to the I-A region of the mouse MHC (1,2) and correlates with mouse Ia specificity 17 or 18. Thus, the determinant recognized by ABIN133240is polymorphic in the mouse. This antibody may be useful for recognizing the rat Ia antigen and can be coupled to Sepharose 4B for purification of rat Ia antigen by antibody affinity chromatography (1). |
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| Immunogen | rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-AG4 (NS1/1) Specificity Rat RT1.B (Rat Ia-non-polymorphic) . Donor: BALB/c spleen |
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| Other Names | RT1.B |
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| Gene, Accession # | Gene ID: 309622 |
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| Catalog # | ABIN133240 |
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| Price | |
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| Order / More Info | RT1 Class II, Locus Bb (RT1-BB) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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