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| Antigenic Specificity | RT1 Class II, Locus Bb (RT1-BB) |
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| Clone | OX-3 |
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| Host Species | Mouse |
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| Reactive Species | mouse, rat |
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| Isotype | IgG1 |
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| Format | phycoerythrin (PE) conjugate |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | Flow Cytometry (FACS) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | anti-rat RT1.Bu monoclonal antibody recognizes a polymorphic determinant on rat Ia present on Lewis, Wistar, and AO rat strains (although it is apparently expressed in lower amounts in AO rats) but not BN, ACI, DA, or PVG/ c strains (1,2). This antibody also cross-reacts with mouse strains (MHC haplotypes b and s ) and analysis of recombinant mouse strains shows that the determinant maps to the I-A region and correlates with mouse Ia specificity 9 (1). ABIN133227recognizes Ia antigens on approximately 18% of thymocytes but does not significantly label the majority of peripheral T lymphocytes (1,3,4). Thus, ABIN133227is particularly useful for distinguishing Ia positive cells from different rat strains and has been used in the recognition of cells of donor origin in bone marrow reconstituted radiation chimeras (3,4). |
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| Immunogen | Rat thymocyte membrane glycoprotein . Fusion Partner: P3-NS1-1-Ag4 (NS1/1) . Donor: BALB/c spleen |
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| Other Names | RT1.B |
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| Gene, Accession # | Gene ID: 309622 |
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| Catalog # | ABIN133227 |
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| Price | |
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| Order / More Info | RT1 Class II, Locus Bb (RT1-BB) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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