产品详情 |
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Antigenic Specificity | PKA RIIalpha |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 40 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The cAMP-dependent protein kinase (PKA) is a critical kinase involved in numerous biological functions. The PKA holoenzyme is composed of two regulatory and two catalytic subunits designated as PKA R and PKA C respectively. PKA R subunits exist as two classes, RI and RII, each containing two isoforms, alpha and beta. On the other hand, PKA C has three identified subunit isoforms, Calpha, Cbeta, and Cgamma, have been identified. The PKA R subunits allow a range of modifying agents to influence PKA activity and localization. They are found in different levels with tissue specificity. Following the bindings between PKA R subunits and the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates many cellular functions such as metabolism, ion transport, and gene transcription.Rabbit Anti-PKA RIIalpha Polyclonal Antibody is developed in rabbit using a synthetic peptide (KLH-coupled) derived from human PKA regulatory IIalpha subunit (PKA RIIalpha). |
Immunogen | Synthetic peptide (KLH-coupled) derived from human PKA regulatory IIα subunit (PKA RIIα) |
Other Names | n/a |
Gene, Accession # | n/a |
Catalog # | ABIN1573985 |
Price | |
Order / More Info | PKA RIIalpha Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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