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| Product Name | Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) (Active) protein |
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| Description | MIP-1 alpha/CCL3, also known as LD78 alpha, is an inflammatory chemokine. MIP-1alpha belongs to the CCL chemokine family, and shares 68% homology with MIP-1beta. The mature form of MIP-1alpha contains 69 amino acids, exists as dimers in solution, and tends to undergo reversible aggregation. The receptors of MIP-1alpha in vivo are mainly the G-protein coupled receptors CCR1 and CCR5. Upon stimulation by endogenous and exogenous agents such as Interleukin-1beta, Interferon-gamma, and lipoteichoic acid from Gram-positive bacteria, monocytes are able to secrete significant amounts of MIP-1alpha. MIP-1alpha augments the adhesions of T lymphocytes, monocytes, and neutrophils to vascular cell adhesion molecule 1. In addition, in wounds, MIP-1alpha chemo-attracts macrophages in order to accelerate the tissue repair process.Recombinant human MIP-1 alpha/CCL3 (rhMIP-1 alpha) produced in E. coli is a single non-glycosylated polypeptide chain containing 70 amino acids. A fully biologically active molecule, rhMIP-1 alpha has a molecular mass of 7.8 kDa analyzed by reducing SDS-PAGE. Synonyms: Macrophage Inflammatory Protein-1 alpha, CCL3, LD78 alpha |
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| Size | 50 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | MIP-1alpha|G0S19-1|LD78ALPHA|MIP-1-alpha|MIP1A|SCYA3|MIP-1a|Scya3|AI323804|LD78alpha|MIP1-(a)|MIP1-alpha|Mip1a|CCL3L1|CCL3L3 |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | ABIN2018252 |
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| Order / More Info | Chemokine (C-C Motif) Ligand 3 (CCL3) (AA 23-92) (Active) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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