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| Product Name | Plasminogen Activator Inhibitor Type 1, wild type active, Murine (PAI-1) |
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| Description | Purified (> 98% pure by SDS PAGE).Activity: 80 ± 5% active by uPA titration. Plasminogen Activator Inhibitor 1 (PAI-1) is a glycoprotein found in plasma that is implicated in the processes of angiogenesis, hemostasis, tumor metastasis, fibrionlysis, ovulation, embryonic development and inflammation (1). The elevation of PAI-1 has shown to correlate with the prognosis of many cancers including breast cancer (2,3,4). PAI-1 is activated by the glycoprotein vitronectin. Vitronectin binds to PAI-1 and modulates fibrinolysis and cell migration (5). This binding has proven to be an important inhibitor of the activated form of protein C (APC) (6). |
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| Size | 500ug |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | n/a |
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| Gene, Accession, CAS # | n/a |
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| Catalog # | P4256-29U |
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| Order / More Info | Plasminogen Activator Inhibitor Type 1, wild type active, Murine (PAI-1) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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