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| Product Name | RNF34, 1-373aa, Human, His tag, E.coli |
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| Description | Purity: > 90% by SDS - PAGE Format: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 10% glycerol 0.1M NaCl, 1mM DTT . RNF34contains a RINF finger, a motif known to be involved in protein-protein and protein-DNA interactions. This protein interacts with DNAJA3/hTid-1, which is a DnaJ protein reported to function as a modulator of apoptosis. Overexpression of this gene in Hela cells was shown to confer the resistance to TNF-alpha induced apoptosis, suggesting an anti-apoptotic function of this protein. This protein can be cleaved by caspase-3 during the induction of apoptosis. This protein also targets p53 and phospho-p53 for degradation. Alternatively splicing results in multiple transcript variants encoding distinct isoforms. Recombinant human RNF34 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
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| Size | 0.5mg, 100ug, 20ug |
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| Concentration | n/a |
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| Applications | SDS-PAGE |
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| Other Names | E3 ubiquitin-protein ligase RNF34 isoform 1, CARP-1, CARP1, Caspase regulator CARP1, Caspases-8 and-10-associated RING finger protein 1, E3 ubiquitin-protein ligase, ring finger protein 34, FLJ21786, RIF, RIFF, E3 ubiquitin protein ligase RNF34 isoform 1 |
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| Gene, Accession, CAS # | NP 919247 |
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| Catalog # | ATGP2419 |
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| Order / More Info | RNF34, 1-373aa, Human, His tag, E.coli from ATGen |
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| Product Specific References | n/a |
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