产品详情 |
Edit |   |
Antigenic Specificity | Dopamine Receptor D1 (DRD1) (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 0.25 mg |
Concentration | n/a |
Applications | Immunohistochemistry (Frozen Sections) (IHC (fro)),Enzyme Immunoassay (EIA),Immunoprecipitation (IP),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Five types of dopamine receptors designated as (dopamine D1-dopamine D5) have been characterized based on cDNA cloning, ligand binding and behavioral responses to antagonist/agonists. Molecular cloning of dopamine receptors have identified a family of closely related genes that encodes 5 proteins with some splice variants exhibiting high degree of amino acid homology (45% -65%) all in the molecular weight range of 40-60 kDa. Individual members of the dopamine receptor family have predicted secondary structure having 7 transmembrane spanning helical domains characteristic feature of G-protein coupled receoptors. Stimulation of dopamine D1 receptor led to Gs coupled adenylate cyclase activation resulting in significant increase in camp levels. All dopamine receptors proteins are glycosylated at or near the C-terminus and are present on either cell surface or in intracellular sites. Some transporters exhibit dynamic trafficking between intracellular storage sites and plasma membranes in response to various stimuli. Dopamine receptors are believed to be associated with other proteins including members of the dopamine receptors and opiod receptors resulting in a significant increase in their apparent molecular weight.Synonyms: D(1A) dopamine receptor, DRD1 |
Immunogen | Peptide |
Other Names | Dop1|drd1|Cak|Drd1|PTK3D|DRD1|DADR|DRD1A|D1a|Drd-1|Drd1a|D1A|C030036C15Rik|Gpcr15 |
Gene, Accession # | Gene ID: 13488,24316 |
Catalog # | ABIN2712089 |
Price | |
Order / More Info | Dopamine Receptor D1 (DRD1) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
产品资料 |
|
|