产品详情 |
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Antigenic Specificity | RB1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | RB1 Antibody is a Rabbit Polyclonal antibody against RB1. The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. |
Immunogen | A synthetic peptide of human RB1. |
Other Names | OSRC; RB; p105-Rb; pRb; pp110; RB1; pp105; Rb-1; Retinoblastoma-associated protein; retinoblastoma 1 |
Gene, Accession # | RB1, Gene ID: 5925, SwissProt: P06400 |
Catalog # | abx001728 |
Price | |
Order / More Info | RB1 Antibody from ABBEXA |
Product Specific References | n/a |
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