| 产品详情 |
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| Antigenic Specificity | RB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer.[1] One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins.[2][3] Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from human RB1. |
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| Immunogen | Human RB1. |
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| Other Names | OSRC; RB; p105-Rb; pRb; pp110; RB1; pp105; Rb-1; Retinoblastoma-associated protein; retinoblastoma 1 |
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| Gene, Accession # | Accession: NP_000312.2, SwissProt: P06400 |
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| Catalog # | abx032759 |
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| Price | |
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| Order / More Info | RB1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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