产品名称 RB1 Antibody from ABBEXA
产品货号 abx032759
产品价格 现货询价,电话:010-67529703
产品规格 80 µl, 400 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityRB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpeptide affinity purified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsWB, IHC, IF/ICC. RUO
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe retinoblastoma protein is a tumor suppressor protein that is dysfunctional in many types of cancer.[1] One highly studied function of pRb is to prevent excessive cell growth by inhibiting cell cycle progression until a cell is ready to divide. pRb belongs to the pocket protein family, whose members have a pocket for the functional binding of other proteins.[2][3] Should an oncogenic protein, such as those produced by cells infected by high-risk types of human papillomaviruses, bind and inactivate pRb, this can lead to cancer. Retinoblastoma (RB) is an embryonic malignant neoplasm of retinal origin. It almost always presents in early childhood and is often bilateral. This RB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-615 amino acids from human RB1.
ImmunogenHuman RB1.
Other NamesOSRC; RB; p105-Rb; pRb; pp110; RB1; pp105; Rb-1; Retinoblastoma-associated protein; retinoblastoma 1
Gene, Accession #Accession: NP_000312.2, SwissProt: P06400
Catalog #abx032759
Price
Order / More InfoRB1 Antibody from ABBEXA
Product Specific Referencesn/a
产品资料