产品名称 RB Antibody from ABBEXA
产品货号 abx011911
产品价格 现货询价,电话:010-67529703
产品规格 100 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityRB
Clonemonoclonal
Host SpeciesMouse
Reactive Specieshuman
IsotypeIgG1
Formatascites
Size100 µl
Concentrationn/a
ApplicationsELISA, IHC. RUO
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionThe Rb protein regulates differentiation, apoptosis, and cell cycle control by coordinating the cell cycle at G1-S with transcriptional machinery. During G1, cyclin D-dependent kinase-mediated phosphorylation of Rb at Ser-795 marks the conversion of Rb from a transcriptionally repressive, hypophosphorylated state to an inactive, phosphorylated state, which may be sustained through mitosis by differential phosphorylation of up to 16 putative serine or threonine residues. Pediatric cancer retinoblastoma and the formation of other human tumors can be attributed to mutations in the retinoblastoma tumor suppressor gene (Rb).
ImmunogenPurified recombinant fragment of human RB expressed in E. Coli.
Other NamesRB; pRb; OSRC; pp110; p105-Rb; RB1; rb; Retinoblastoma-associated protein
Gene, Accession #RB1, Gene ID: 5925, SwissProt: P06400
Catalog #abx011911
Price
Order / More InfoRB Antibody from ABBEXA
Product Specific Referencesn/a
产品资料