产品详情 |
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Antigenic Specificity | Rb1 |
Clone | 1F8 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | peroxidase (HRP) conjugate |
Size | 50 ul |
Concentration | n/a |
Applications | IHC-Fr, IP, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse monoclonal to Rb1 (HRP). This antibody recognises retinoblastoma-associated protein (RB), a 105kDa tumour suppressor which is also known as Rb1. Rb1 functions as a transcription factor that controls cell cycle progression (at the G1/S phase transition) through its repression of E2F-mediated transcription. Mutation of the Rb gene is found frequently in human sarcomas, lung, bladder and breast carcinomas and is the molecular basis for hereditary disposition to retinoblastoma. |
Immunogen | Human Rb gel purified from bacterial lysates |
Other Names | OSRC, p105-Rb, pp110, pRb, Rb, RB1, retinoblastoma 1, retinoblastoma suspectibility protein, Retinoblastoma-associated protein |
Gene, Accession # | Gene ID: 5925, UniProt: P06400 (Human); P13405 (Mouse) |
Catalog # | orb223741 |
Price | |
Order / More Info | Rb1 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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