产品名称 RB1 Antibody from BIORBYT LTD.
产品货号 orb66933
产品价格 现货询价,电话:010-67529703
产品规格 100 ul
产品品牌 BIORBYT LTD.
产品概述
产品详情
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Antigenic SpecificityRB1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formataffinity purified
Size100 ul
Concentrationn/a
ApplicationsWB
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DescriptionRabbit polyclonal to RB1.Retinoblastoma-associated protein b) is a tumor suppressor and a key regulator of entry into celldivision. RB1 acts as a transcription repressor of E2F1 target genes. The hypophosphorylated, activeform of RB1 interacts with E2F1 and represses its transcription activity, leading to cell cycle arrest.RB1 is directly involved in heterochromatin formation by maintaining overall chromatin structure and,in particular, that of constitutive heterochromatin by stabilizing histone methylation. When it is time fora cell to enter S phase, complexes of cyclin-dependent kinases (CDK) and cyclins phosphorylate RB1and inhibit its activity.
Immunogenmiddle region of human RB1
Other NamesRB1,Retinoblastomaassociated protein,p105Rb,pRb,pp110,Rb
Gene, Accession #UniProt: P06400
Catalog #orb66933
Price
Order / More InfoRB1 Antibody from BIORBYT LTD.
Product Specific Referencesn/a
产品资料