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| Antigenic Specificity | Dopamine Receptor D3 (DRD3) (aa 352-367), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | DRD3 is a dopamine receptor that differs in its pharmacology and signaling system from the D1 and D2 receptors and represents both an autoreceptor and a postsynaptic receptor. DRD3 is localized to limbic areas of the brain, which are associated with cognitive, emotional, and endocrine functions. The DRD3 gene, which is mapped to chromosome 3, is like the DRD2 gene but unlike most other members of this superfamily and it contains introns, 5 in number. The position of 2 of the introns corresponds to that of introns in DRD2. The D3 receptor appeared to mediate some of the effects of antipsychotic drugs and drugs used in the treatment of Parkinson disease, which were previously though to interact only with D2 receptors. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Dopamine Receptor D3(352-367aa NTHCQTCHVSPELYSA), different from the related rat and mouse sequences by two amino acids. |
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| Other Names | DRD3|D3R|D3DR|ETM1|FET1 |
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| Gene, Accession # | Gene ID: 1814,29238 |
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| Catalog # | ABIN1673058 |
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| Price | |
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| Order / More Info | Dopamine Receptor D3 (DRD3) (aa 352-367), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1916765, 1975644 |
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