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| Antigenic Specificity | Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (aa 318-415) |
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| Clone | S56A-50 |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, rat, Xenopus laevis, zebrafish |
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| Isotype | n/a |
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| Format | alkaline phosphatase (AP) conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Immunoprecipitation (IP),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CASK (calmodulin sensitive kinase) is a ~112kDa member of the membrane associated quanylate kinase (MAGUK) protein family. It is an adaptor protein with a calcium/calmodulin-dependent protein kinase domain, a SH3 domain, aguanylate kinase homology domain (GUK) and a PDZ domain. CASK links transmembrane proteins to the cytoskeleton and signaling molecules. In particular, CASK binds to Neurexin to stabilize pre- and post-synaptic structrures. While most of CASK proteins are cytoplasmic, a portion of the protein enters the nucleus, where it acts as a transcriptional co-activator. Manifesting the importance of CASK, transgenic mice with insertional mutations die within 24 hours of births. CASK is also localized in the nuclei of basal keratinocytes in newborn rodent skin and developing hair follicles. It may play a role in wound healing.Cellular Localization: Membrane |
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| Immunogen | Fusion protein amino acids 318-415 of rat CASK/Lin2 |
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| Other Names | CAKI|CAMGUK|CG13412|CG13413|CG6703|CMG|CMG/CASK|Caki|CamGUK|CamguK|Camguk|Cask|Cmg|DLin-2|Dmel\\CG6703|RE09582p|caki|camguk|cmg|dCASK|wu:fb70g06|CAGH39|FGS4|LIN2|MICPCH|MRXSNA|TNRC8|DXPri1|DXRib1|LIN-2|Pals3|mLin-2 |
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| Gene, Accession # | Gene ID: 259195,446996,8573,12361,29647 |
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| Catalog # | ABIN2483418 |
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| Price | |
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| Order / More Info | Calcium/calmodulin-Dependent serine Protein Kinase (MAGUK Family) (CASK) (aa 318-415) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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