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| Antigenic Specificity | Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (aa 18-33), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CXCR4 is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1, it functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. Tachibana et al.(1998) conclude that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR4(18-33aa SGDYDSMKEPCFREEN), different from the related rat and mouse sequences by two amino acids. |
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| Other Names | CXC-R4|CXCR-4|cd184|d2s201e|fb22|hm89|hsy3rr|lap3|lcr1|lestr|npy3r|npyr|npyrl|npyy3r|whim|xcxcr4|cxcr4|CD184|Cmkar4|LESTR|PB-CKR|PBSF/SDF-1|Sdf1r|D2S201E|FB22|HM89|HSY3RR|LAP3|LCR1|NPY3R|NPYR|NPYRL|NPYY3R|WHIM|CXC-R4-B|CXCR-4-B|CXCR4|cb403|zgc:109863 |
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| Gene, Accession # | Gene ID: 7852,60628 |
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| Catalog # | ABIN343363 |
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| Price | |
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| Order / More Info | Chemokine (C-X-C Motif) Receptor 4 (CXCR4) (aa 18-33), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 22902648, 21738044, 20349215, 19438749, 17415525, 17046575, 9634237, 9599023 |
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