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Antigenic Specificity | Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (aa 331-351), (C-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | immunogen affinity purified |
Size | 100 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CXCR6(Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al.(1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al.(2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al.(2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation. |
Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of mouse Bonzo(331-351aa EDSSKTCSASHNVETTSMFQL), different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids |
Other Names | BONZO|CD186|STRL33|TYMSTR|BB217514 |
Gene, Accession # | Gene ID: 80901,100124593 |
Catalog # | ABIN1673566 |
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Order / More Info | Chemokine (C-X-C Motif) Receptor 6 (CXCR6) (aa 331-351), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 11017100, 11238560, 9166430 |
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