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Antigenic Specificity | CD68 Molecule (CD68) |
Clone | Y1-82A |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2b |
Format | unconjugated |
Size | 100 tests |
Concentration | n/a |
Applications | Flow Cytometry (FACS),Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD68 (also known as LAMP4 or SCARD1) is a 110 kDa type I transmembrane glycoprotein of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and the scavenger receptor family. Although CD68 primarily localizes to lysosomes and endosomes, its fraction circulates to the cell surface. By the heavily glycosylated extracellular domain CD68 binds to tissue- and organ-specific lectins or selectins. It is expressed mainly in cytoplasmic granules of monocytes/macrophages, granulocytes, and dendritic cells, but also e.g. in a proportion of epithelial tumours (diagnosis of poorly differentiated neoplasms). |
Immunogen | Lysosomal contents of lung macrophages |
Other Names | Lamp4|Scard1|gp110|GP110|LAMP4|SCARD1 |
Gene, Accession # | Gene ID: 968 |
Catalog # | ABIN2749210 |
Price | |
Order / More Info | CD68 Molecule (CD68) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |