产品详情 |
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Antigenic Specificity | ACVRL1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | purified |
Size | 80 µl, 400 µl |
Concentration | n/a |
Applications | WB, IHC, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2. This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-68 amino acids from the N-terminal region of human ACVRL1. |
Immunogen | Human ACVRL1. |
Other Names | ACVRL1; ACVRLK1; ALK1; Serine/threonine-protein kinase receptor R3; Activin receptor-like kinase 1; TGF-B superfamily receptor type I; ALK-1; TSR-I |
Gene, Accession # | Accession: NP_000011.2, NP_001070869.1, SwissProt: P37023 |
Catalog # | abx033693 |
Price | |
Order / More Info | ACVRL1 Antibody from ABBEXA |
Product Specific References | n/a |
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