产品详情 |
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Antigenic Specificity | AIRE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB, IF/ICC. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | AIRE Antibody is a Rabbit Polyclonal antibody against AIRE. This gene encodes a transcriptional regulator that forms nuclear bodies and interacts with the transcriptional coactivator CREB binding protein. The encoded protein plays an important role in immunity by regulating the expression of autoantigens and negative selection of autoreactive T-cells in the thymus. Mutations in this gene cause the rare autosomal-recessive systemic autoimmune disease termed autoimmune polyendocrinopathy with candidiasis and ectodermal dystrophy (APECED). [provided by RefSeq, Jun 2012]. |
Immunogen | A synthetic peptide of human AIRE. |
Other Names | AIRE; AIRE (Ab-156); AIRE1; APECED; APECED protein; APS1; APSI; Autoimmune polyendocrinopathy candidiasis ectodermal dystrophy protein; Autoimmune regulator; PGA1; autoimmune polyendocrinopathy candidiasis ectodermal dystrophy |
Gene, Accession # | AIRE, Gene ID: 326, SwissProt: O43918 |
Catalog # | abx001466 |
Price | |
Order / More Info | AIRE Antibody from ABBEXA |
Product Specific References | n/a |
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