产品详情 |
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Antigenic Specificity | Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | MKK3 and MKK6 are two closely related dual-specificity protein kinases that activate p38 MAP kinase . MKK3 and MKK6 both phosphorylate and activate p38 MAP kinase at its activation site, Thr-Gly-Tyr, but do not phosphorylate or activate Erk1/2 or SAPK/JNK. Phosphorylation of p38 MAP kinase dramatically stimulates its ability to phosphorylate protein substrates such as ATF-2 and Elk-1. MKK3 and MKK6 are both activated by different forms of cellular stress and inflammatory cytokines . Activation of MKK3 and MKK6 occurs through phosphorylation of Ser189 and Thr193 on MKK3 and Ser207 and Thr211 on MKK6 . Synonyms: MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2, |
Immunogen | A phospho specific peptide corresponding to residues surrounding pSer189 of human MAP2K3 |
Other Names | Mkk3|MAPKK3|MEK3|MKK3|PRKMK3|SAPKK-2|SAPKK2|AW212142|Prkmk3|mMKK3b|map2k3|zMKK3 |
Gene, Accession # | Gene ID: 5606,26397,303200 |
Catalog # | ABIN1684162 |
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Order / More Info | Mitogen-Activated Protein Kinase Kinase 3 (MAP2K3) (pSer189) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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