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| Antigenic Specificity | Bassoon (BSN) (aa 786-1041), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | PE-Atto 594 conjugate |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors.Cellular Localization: Cytoplasm | Cell Junction | Synapse |
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| Immunogen | NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein |
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| Other Names | Znf231|ZNF231 |
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| Gene, Accession # | Gene ID: 12217,29138 |
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| Catalog # | ABIN2484545 |
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| Price | |
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| Order / More Info | Bassoon (BSN) (aa 786-1041), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 20127803 |
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