产品详情 |
Edit |   |
Antigenic Specificity | Bassoon (BSN) (aa 786-1041), (N-Term) |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | Atto 680 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Bassoon is a 420 kDa protein that is a localized at the presynaptic nerve terminals and is believed to play a role in the structural and functional organization of the synaptic vesicle cycle. Bassoon is predicted to contain two double-zinc fingers, three coiled-coil regions, and two polyglutamine domains. The polyglutamine domains in the C-terminus are of interest, since it is known that for some human proteins, such as Huntington, abnormal amplification of this region can cause late-onset neurodegeneration. Bassoon is concentrated at sites opposite to postsynaptic densities in synaptic terminals and in cultured neurons, it is found to co-localize with GABA (A) and glutamate (GluR1) receptors.Cellular Localization: Cytoplasm | Cell Junction | Synapse |
Immunogen | NM_003458.3 (AA 786-1041) N-terminal his-tagged fusion protein |
Other Names | Znf231|ZNF231 |
Gene, Accession # | Gene ID: 12217,29138 |
Catalog # | ABIN2484538 |
Price | |
Order / More Info | Bassoon (BSN) (aa 786-1041), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 20127803 |
产品资料 |
|
|