| 产品详情 |
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| Antigenic Specificity | CTNNB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CTNNB1 Antibody is a Rabbit Polyclonal antibody against CTNNB1. The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. |
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| Immunogen | A synthetic peptide of human CTNNB1. |
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| Other Names | catenin (cadherin-associated protein); beta 1; 88kDa; CTNNB1; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; ?? catenin; BETA catenin; b-cat; CATNB; CTNB1; catenin; beta; β-catenin; MRD19; armadillo; Catenin beta-1; Beta-catenin; OK/SW-cl.35; PRO2286 |
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| Gene, Accession # | CTNNB1, Gene ID: 1499, SwissProt: P35222 |
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| Catalog # | abx001681 |
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| Price | |
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| Order / More Info | CTNNB1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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