| 产品详情 |
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| Antigenic Specificity | CTNNB1 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | peptide affinity purified |
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| Size | 80 µl, 400 µl |
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| Concentration | n/a |
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| Applications | WB, IHC, IF/ICC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. This CTNNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 692-721 amino acids from the C-terminal region of human CTNNB1. |
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| Immunogen | Human CTNNB1. |
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| Other Names | catenin (cadherin-associated protein); beta 1; 88kDa; CTNNB1; CTNNB; DKFZp686D02253; FLJ25606; FLJ37923; ?? catenin; BETA catenin; b-cat; CATNB; CTNB1; catenin; beta; β-catenin; MRD19; armadillo; Catenin beta-1; Beta-catenin; OK/SW-cl.35; PRO2286 |
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| Gene, Accession # | CTNNB1, SwissProt: P35222 |
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| Catalog # | abx034617 |
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| Price | |
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| Order / More Info | CTNNB1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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