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Antigenic Specificity | CD4 Molecule (CD4) |
Clone | Edu-2 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | purified |
Size | 1 mL |
Concentration | n/a |
Applications | Flow Cytometry (FACS),Immunocytochemistry (ICC),Immunohistochemistry (Frozen Sections) (IHC (fro)),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD4 (Cluster of Differentiation 4) is a glycoprotein expressed on the surface of T helper cells, monocytes, macrophages, and dendritic cells. It was discovered in the late 1970s and was originally known as leu-3 and T4 (after the OKT4 monoclonal antibody that reacted with it) before being named CD4 in 1984. In humans, the CD4 protein is encoded by the CD4 gene. CD4 plays a role in the recognition of foreign antigens presented to T cells by MHC class II molecules. Furthermore, this antigen acts as a receptor for HIV-1 by binding the viral protein gp120. The CD4 antigen is present on most thymocytes and a subpopulation of peripheral blood T cells, called T helper cells (Th). In addition, CD4 is expressed on monocytes and weak on macrophages. |
Immunogen | n/a |
Other Names | cd4|L3T4|Ly-4|CD4mut|W3/25|p55 |
Gene, Accession # | Gene ID: 920 |
Catalog # | ABIN1042376 |
Price | |
Order / More Info | CD4 Molecule (CD4) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 6408167, 3531334, 6800422, 2439105 |
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