产品名称 CKIP-1 Antibody from ABBEXA
产品货号 abx033969
产品价格 现货询价,电话:010-67529703
产品规格 80 µl, 400 µl
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityCKIP-1
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatpurified
Size80 µl, 400 µl
Concentrationn/a
ApplicationsWB, IHC, FCM. RUO
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionCKIP-1 plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). This protein may function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). It appears to target ATM to the plasma membrane and appears to also inhibit tumor cell growth by inhibiting AKT-mediated cell-survival. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation. This CKIP-1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 49-77 amino acids from the N-terminal region of human CKIP-1.
ImmunogenHuman CKIP-1.
Other NamesPLEKHO1; CKIP1; Pleckstrin homology domain-containing family O member 1; C-Jun-binding protein; Casein kinase 2-interacting protein 1; Osteoclast maturation-associated gene 120 protein
Gene, Accession #SwissProt: Q53GL0
Catalog #abx033969
Price
Order / More InfoCKIP-1 Antibody from ABBEXA
Product Specific Referencesn/a
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