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| Product Name | NOX4, GST-Tag, Recombinant (KOX, KOX-1, RENOX, NADPH Oxidase 4) |
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| Description | Lysate. Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 4 displays an increased activity. Isoform 5 and isoform 6 display reduced activity. Source: Partial length protein corresponding to of NOX4, fused to GST-Tag at N-terminal, expressed in E. coli. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Molecular Weight: ~39kD |
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| Size | 200ug |
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| Concentration | n/a |
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| Applications | WB |
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| Other Names | n/a |
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| Gene, Accession, CAS # | NOX4, Gene ID: 50507, Accession: NP_058627, SwissProt: Q9NPH5 |
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| Catalog # | 500852 |
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| Order / More Info | NOX4, GST-Tag, Recombinant (KOX, KOX-1, RENOX, NADPH Oxidase 4) from UNITED STATES BIOLOGICAL |
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| Product Specific References | n/a |
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