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| Product Name | STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) protein |
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| Description | CHIP, also known as STUB1, is a cytoplasmic protein whose amino acid sequence is highly conserved across species. CHIP interacts with the molecular chaperones Hsc70-Hsp70 and Hsp90 through its TPR domain, whereas its U-box domain contains its E3 ubiquitin ligase activity. Its interaction with these molecular chaperones results in client substrate ubiquitylation and degradation by the proteasome. Thus, CHIP acts to tilt the folding-refolding machinery toward the degradative pathway, and it serves as a link between the two. Recombinant human CHIP protein was expressed in E. coli and purified by using conventional chromatography techniques. Alternative Names: NY CO 7 protein, STUB 1 protein, CHIP protein, HSPABP2 protein, STIP1 homology and U Box containing protein 1., E3 ubiquitin protein ligase CHIP protein, STUB1 protein, UBOX1 protein, Carboxy terminus of HSP70 interacting protein protein NY CO 7 protein, SDCCAG7 protein, UBOX 1 protein, NY-CO-7 protein, Carboxy terminus of Hsp70p interacting protein protein, Serologically defined colon cancer protein 7 protein, CLL associated protein KW 8 protein, Heat shock protein A binding protein 2 (c terminal) protein |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | SDS-PAGE (SDS) |
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| Other Names | STUB1|chip|ATCHIP|CARBOXYL TERMINUS OF HSC70-INTERACTING PROTEIN|carboxyl terminus of HSC70-interacting protein|0610033N24Rik|2210017D18Rik|2310040B03Rik|AW046544|Chip|wu:fc22f04|zgc:56076|CHIP|HSPABP2|NY-CO-7|SDCCAG7|UBOX1 |
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| Gene, Accession, CAS # | Gene ID: 10273 |
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| Catalog # | ABIN935009 |
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| Order / More Info | STIP1 Homology and U-Box Containing Protein 1 (STUB1) (AA 1-303) protein from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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