| 产品详情 |
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| Product Name | Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) (AA 33-530) protein (His tag) |
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| Description | Platelet-Derived Growth Factor Receptor beta (PDGFR-beta) is a member of the protein kinase superfamily and CSF-1/PDGF receptor subfamily. The PDGF family consists of PDGF-A, -B, -C and -D, which form either homo- or heterodimers (PDGF-AA, -AB, -BB, -CC, -DD). The four PDGFs are inactive in their monomeric forms. The PDGFs bind to the protein tyrosine kinase receptors PDGF receptor-alpha and -beta. These two receptor isoforms dimerize upon binding the PDGF dimer, leading to three possible receptor combinations, namely -alphaalpha, -betabeta and -alphabeta. The extracellular region of the PDGF receptor-beta consists of five immunoglobulin-like domains while the intracellular part is a tyrosine kinase domain. In addition to being a potent mitogen for cells of mesenchymal origin, PDGF has also been shown to be a potent chemoattractant for mesenchymal cells, mononuclear cells, and neutrophils and has been reported to be important in the modification of cellular matrix constituents.Alternative Names: Platelet-Derived Growth Factor Receptor Beta, PDGF-R-Beta, PDGFR-Beta, Beta Platelet-Derived Growth Factor Receptor, Beta-Type Platelet-Derived Growth Factor Receptor, CD140 Antigen-Like Family Member B, Platelet-Derived Growth Factor Receptor 1, PDGFR-1, |
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| Size | 10 µg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | AI528809|CD140b|PDGFR-1|Pdgfr|CD140B|IBGC4|JTK12|PDGFR|PDGFR1 |
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| Gene, Accession, CAS # | Gene ID: 5159 |
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| Catalog # | ABIN1097304 |
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| Order / More Info | Platelet-Derived Growth Factor Receptor, beta Polypeptide (PDGFRB) (AA 33-530) protein (His tag) from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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